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Daniela Badita

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Articles signed on Romanian Journal of RHEUMATOLOGY:

PERIODONTAL HEALTH STATUS EVALUATION USING CPITN SCORE, IN A GROUP OF PATIENTS WITH RHEUMATOID ARTHRITIS

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Romanian Journal of Rheumatology, Volume XXIV, No. 4, 2015
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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PERIODONTAL HEALTH STATUS EVALUATION USING CPITN SCORE, IN A GROUP OF PATIENTS WITH RHEUMATOID ARTHRITIS

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ABSTRACT

Introduction. The relationship between periodontal disease (PD) and rheumatoid arthritis (RA) is currently only partially known, both being chronic multifactorial diseases that may share common pathogenic mechanisms and etiological factors. In a previous meta-analysis we concluded that patients with RA are more commonly affected by PD and develop more severe forms of the disease, compared to the general population.
Objectives. The current study aimed to assess the degree of periodontal damage and oral hygiene on a group of patients diagnosed with RA.
Methods. The study was conducted on a group of 30 patients, 6 sextants being assessed in each patient (180 potentially evaluable sextants). Establishing the degree of periodontal damage and oral hygiene was achieved by determining the Community Periodontal Index of Treatment Needs (CPITN) and Oral Hygiene Index (IHB, also known as OHI).
Results. The mean CPITN score/sextant was 1.92. After clinical examination we found 10 edentulous sextants that could not be evaluated. As a result of the distribution of the scores on all the 170 evaluable sextants, we obtained: CPITN 0 – 11.1%, CPITN 1 – 23.6%, CPITN 2 – 32.4%, CPITN 3 – 27.6%, CPITN 4 – 5.3%. After analyzing the oral hygiene index the mean value we found was 16. Distribution of IHB intervals was: IHB 0-12 (40%), IHB 13-24 (53.3%), IHB 25-36 (6.6%).
Discussion and conclusions. Comparing our results to data from the literature, in our group of patients with RA the only CPITN index criteria significantly increased, compared to the healthy population, were gingival bleeding on probing and the number of periodontal pockets with 4-5.5 mm depth.

Keywords: periodontal disease, rheumatoid arthritis, CPITN, IHB

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PERIODONTAL DISEASE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: CARDIOVASCULAR RISK AND SIDE EFFECTS OF CORTICOTHERAPY INVOLVING ORAL HEALTH

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Romanian Journal of Rheumatology, Volume XXIV, No. 3, 2015
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJR has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

PERIODONTAL DISEASE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: CARDIOVASCULAR RISK AND SIDE EFFECTS OF CORTICOTHERAPY INVOLVING ORAL HEALTH

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ABSTRACT

Systemic lupus erythematosus (SLE) and periodontal disease (PD) are two chronic inflammatory diseases that share common pathogenetic mechanisms. Therefore, it is thought that a correlation between the two pathologies might exist. PD itself, when not associated with SLE, does not cause major cardiovascular events, but it contributes to the development of atherosclerosis, which is the major cause of death among patients with SLE. This article aims to summarize the available literature concerning the association between these two disorders (PD prevalence in patients with SLE, correlations between periodontal damage and SLEDAI activity score), to present the main mechanisms by which the two pathologies affect the cardiovascular system and to evaluate the impact of SLE corticosteroid therapy on periodontal tissue.

Keywords: systemic lupus erythematosus, periodontal disease, cardiovascular risk, corticotherapy

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FAMILIA CITOKINELOR IL-17 SI SUBPOPULATIILE LIMFOCITARE THCD4+ (TH1, TH17, TREG) – IMPLICATII ÎN PATOLOGIA BOLILOR AUTOIMUNE

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Romanian Journal of Rheumatology, Volume XXIII, No. 2, 2014
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJR has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

FAMILIA CITOKINELOR IL-17 SI SUBPOPULATIILE LIMFOCITARE THCD4+ (TH1, TH17, TREG) – IMPLICATII ÎN PATOLOGIA BOLILOR AUTOIMUNE

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REZUMAT

Citokinele sunt molecule de tip polipeptidic cu funcţii de mesageri intercelulari, având roluri esenţiale în reglarea funcţiilor sistemului imunitar. Principalele subtipuri limfocitare eliberează citokine specifice, prin intermediul cărora îşi îndeplinesc funcţiile caracteristice. Limfocitele T Helper 17 (LTH17) au un rol esenţial în controlul patogenilor extracelulari. Studii recente atrag însă atenţia asupra contribuţiei esenţiale a acestui subtip limfocitar major în declanşarea şi menţinerea unor procese inflamatorii cronice. Astfel, în poliartrita reumatoidă (PR) stadiile iniţiale ale bolii se caracterizează prin selectarea unui anumit fenotip limfocitar, ce sintetizează interleukina-17A (IL-17A), cu efecte proinflamatorii locale semnificative, astfel încât se constată o relaţie de proporţionalitate directă între expresia IL-17 şi distrucţia articulară. De asemenea, interacţiunea dintre IL-17 şi factorul de necroză tumorală (TNF) poate contribui semnificativ la distrucţia tisulară şi la persistenţa sindromului inflamator întâlnite în această afecţiune. Mecanisme similare au fost observate şi în cazul spondilitei anchilozante sau artritei psoriazice. Descoperirea implicaţiilor fiziopatologice ale IL-17 în patogenia bolilor autoimune a condus la deschiderea unor noi orizonturi de tratament, fiind studiate în prezent noi metode de terapie biologică, cu acţiune directă sau indirectă.

Articolul de faţă sintetizează cele mai recente date referitoare la implicarea LTH17, dar şi a limfocitelor T helper 1 (LTH1) şi T reglatorii (LTreg) în patogeneza afecţiunilor autoimune.

Cuvinte cheie: citokine, limfocite, afecţiuni autoimune

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PATHOPHYSIOLOGICAL CORRELATIONS BETWEEN ANKYLOSING SPONDYLITIS AND PERIODONTAL DISEASE. THE IMPACT OF ANKYLOSING SPONDYLITIS THERAPY ON PERIODONTAL TISSUE

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Romanian Journal of Neurology, Volume XXIV, No. 1, 2015
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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DOAJ
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HIGHLIGHTS

National Awards “Science and Research”

NEW! RJR has announced the annually National Award for "Science and Research" for the best scientific articles published throughout the year in the official journal.

ICMJE- Recommendations

Read the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals.

Promoting Global Health

The published medical research literature is a global public good. Medical journal editors have a social responsibility to promote global health by publishing, whenever possible, research that furthers health worldwide.

PATHOPHYSIOLOGICAL CORRELATIONS BETWEEN ANKYLOSING SPONDYLITIS AND PERIODONTAL DISEASE. THE IMPACT OF ANKYLOSING SPONDYLITIS THERAPY ON PERIODONTAL TISSUE

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ABSTRACT

Periodontal disease (PD) and ankylosing spondylitis (AS) are both chronic inflammatory conditions characterized by a destructive process in the deep marginal periodontal tissue and, respectively, in the joints and entheses. This article summarizes all current data regarding the association between PD and AS and assesses the impact of AS therapy on periodontal tissue.

Keywords: ankylosing spondylitis, periodontal disease, TNF-α inhibitors

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