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I. Marin

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  • SINDROM POLIMIALGIC PARANEOPLAZIC LA UN PACIENT CU NEOPLASM GASTRIC - 22/09/2015

Articles signed on Romanian Journal of RHEUMATOLOGY:

SINDROM POLIMIALGIC PARANEOPLAZIC LA UN PACIENT CU NEOPLASM GASTRIC

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Romanian Journal of Rheumatology, Volume XXIII, No. 1, 2014
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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SINDROM POLIMIALGIC PARANEOPLAZIC LA UN PACIENT CU NEOPLASM GASTRIC

Mihaela Milicescu, Teodora Mazdrag, Oana Vutcanu, I. Marin and M. Bojincă

REZUMAT

Polimialgia reumatică (PMR) este o afecţiune caracterizată de dureri şi redoare la nivelul musculaturii proximale a centurilor scapulo-humerale şi coxo-femurale. Boala afectează persoanele cu vârsta peste 50 de ani. Majoritatea pacienţilor prezintă valori crescute ale reactanţilor de fază acută. În practică sunt întâlniţi frecvent pacienţi care se prezintă cu sindroame polimialgice, dar la care diagnosticul este reîncadrat la evaluările ulterioare. Sindroamele paraneoplazice sunt determinate de secreţia hormonilor, peptidelor sau citokinelor de către tumori sau prin imunitatea încrucişată între ţesuturile normale şi cele maligne. Prezentăm cazul unei paciente care la prima evaluare în clinică prezenta manifestări clinice, teste biologice şi modificări imagistice sugestive pentru polimialgia reumatică. Deşi sub tratament corticosteroid se obţine o ameliorare a simptomatologiei, la următoarea evalure se observă o schimbare netă a tabloului clinic, biologic şi imagistic, ceea ce duce la reîncadrarea diagnosticului în sindrom polimialgic paraneoplazic (SPP) secundar unui neoplasm gastric.

Cuvinte cheie: sindrom polimialgic paraneoplazic, polimialgie reumatică

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