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ROWELL SYNDROME – A CONTROVERSIAL CLINICAL ENTITY
Iulia-Tania Andronache, Cristina Şuţa, Claudiu Ionescu, Anca Calistrat and Maria Şuţa
ABSTRACT
Rowell syndrome is considered to be an unusual association between systemic lupus erythematous (SLE), erythema multiforme-like lesions and an immunological pattern consisting of speckled ANA, positive rheumatoid factor and positive anti-La (SSB) antibodies. We present the case of an 81 year old woman with late-onset SLE who developed an erythema multiforme-like rash, with a speckled antinuclear antibodies (ANA) immunofluorescence pattern and a positive rheumatoid factor. The key in establishing the diagnosis was the biopsy of the lesion, which set the diagnosis of Rowell syndrome.
Keywords: Rowell syndrome, systemic lupus erythematous, erythema multiforme