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Romanian Journal of Rheumatology, Volume XXIV, No. 4, 2015
ISSN 1843-0791  |  e-ISSN 2069-6086
ISSN-L 1843-0791
DOI: 10.37897/RJR

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ROWELL SYNDROME – A CONTROVERSIAL CLINICAL ENTITY

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ABSTRACT

Rowell syndrome is considered to be an unusual association between systemic lupus erythematous (SLE), erythema multiforme-like lesions and an immunological pattern consisting of speckled ANA, positive rheumatoid factor and positive anti-La (SSB) antibodies. We present the case of an 81 year old woman with late-onset SLE who developed an erythema multiforme-like rash, with a speckled antinuclear antibodies (ANA) immunofluorescence pattern and a positive rheumatoid factor. The key in establishing the diagnosis was the biopsy of the lesion, which set the diagnosis of Rowell syndrome.

Keywords: Rowell syndrome, systemic lupus erythematous, erythema multiforme

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